Erythropoietin
نویسندگان
چکیده
منابع مشابه
Production of Erythropoietin-specific polyclonal Antibodies
Background: Erythropoietin, as a principal hormone promotes red blood cell production in bone marrow. Varieties of erythropoietin biosimilar are being produced by recombinant DNA technology in cell cultures. The detection or quantification of these molecules are being performed by diff erent methods which some of theme such as Western blot and enzymelinked immunosorbent assay (ELISA) require sp...
متن کاملHuman Cancer Erythropoietin and Erythropoietin Receptor Expression in
Erythropoietin (EPO) stimulates the growth of erythroblasts in the bone marrow (C. Lacombe and P. Mayeux, Nephrol. Dial. Transplant., 14 (Suppl. 2): 22–28, 1999). We report basal and hypoxia-stimulated expression of EPO and its receptor, EPOR, in human breast cancer cells, and we demonstrate EPO-stimulated tyrosine phosphorylation and the proliferation of these cells in vitro. In 50 clinical sp...
متن کاملStudies on erythropoietin. I. Demonstration of erythropoietin in normal plasma.
I T IS NOW generally accepted that erythropoiesis is in part regulated by humoral mechanisms.14 The term erythropoietin has been given to the proposed humoral factor; its chemical nature, physiologic effects and site of formation have been subjects of numerous investigations. Yet no convincing demonstration of its presence in normal plasma has been described. Accordingly, inferences regarding c...
متن کاملErythropoietin and erythropoietin receptor expression in human cancer.
Erythropoietin (EPO) stimulates the growth of erythroblasts in the bone marrow (C. Lacombe and P. Mayeux, NEPHROL: DIAL: TRANSPLANT:, 14 (SUPPL: 2): 22-28, 1999). We report basal and hypoxia-stimulated expression of EPO and its receptor, EPOR, in human breast cancer cells, and we demonstrate EPO-stimulated tyrosine phosphorylation and the proliferation of these cells in vitro. In 50 clinical sp...
متن کاملExpression of erythropoietin and erythropoietin receptor in peritoneal endometriosis.
BACKGROUND Recent studies have indicated new physiological roles for erythropoietin (Epo) unrelated to erythropoiesis. We previously demonstrated that the Epo concentrations in peritoneal fluid from patients with stage I endometriosis were significantly higher than those with stages II, III and IV of the disease. Therefore, we hypothesized that Epo may play a role in the pathogenesis of endomet...
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ژورنال
عنوان ژورنال: Transfusion Alternatives in Transfusion Medicine
سال: 2000
ISSN: 1295-9022,1778-428X
DOI: 10.1111/j.1778-428x.2000.tb00020.x